Own a Pizza Shop in Charleston, Columbia, Greenville, or Myrtle Beach

Looking for the perfect business to invest in—one that brings people together, delivers incredible food, and thrives in both small towns and booming cities? Antioch Pizza Shop is now offering pizza franchise opportunities throughout South Carolina, and we’re searching for franchise partners who want to build something meaningful in their community.

Whether you’re located in Charleston, Columbia, Greenville, Myrtle Beach, Spartanburg, Rock Hill, Summerville, Hilton Head, or anywhere in between, South Carolina is one of the best states in the Southeast to launch a thriving pizza franchise.

Born in the Midwest and voted the #1 Pizza in Chicago (2024), Antioch Pizza Shop is expanding into the South—and South Carolina is at the top of our growth map.

Key Takeaways

• South Carolina is one of the fastest-growing states, offering strong demand for new restaurants and community-focused pizza shops.
• Antioch Pizza Shop is actively seeking franchise partners in Charleston, Columbia, Greenville, Myrtle Beach, and surrounding areas.
• Franchisees choose from four flexible models: full-service, takeout/delivery, express restaurant, and pizza food truck.
• Startup investments are significantly lower than many national chains.
• Antioch Pizza is an award-winning Midwest brand known for fresh ingredients, homemade dough, and a strong community-driven culture.
• Franchise owners receive full training, marketing support, and operational guidance.
• Ideal for franchisees who want a hands-on, community-focused business with room for growth. 

Why South Carolina Is Ripe for a Pizza Franchise

South Carolina is one of the fastest-growing states in the region—making it a prime location for new restaurants and community-driven brands. The state offers:

✔ Rapid population growth

Charleston, Greenville, Fort Mill, and Summerville are among the fastest-growing areas in the Southeast.

✔ A strong tourism economy

Cities like Charleston, Myrtle Beach, and Hilton Head attract millions of visitors annually.

✔ Vibrant college towns

Columbia (USC), Clemson, and Charleston host huge student populations.

✔ Booming suburbs

Greer, Easley, Lexington, and Rock Hill are growing fast, with families seeking new dining options.

This mix of families, students, tourists, and professionals creates ongoing demand for quality pizza—making South Carolina ideal for an Antioch Pizza franchise.

What Makes Antioch Pizza Stand Out?

When you franchise with Antioch Pizza, you’re not just opening another pizza shop—you’re joining a family-focused, food-loving community built on trust and flavor.

Here’s what sets us apart:

• Award-Winning Flavor: Our menu is built around recipes that earned us top honors in Chicago. From our homemade dough and sauces to fresh-cut vegetables and premium toppings, every ingredient is made or prepped in-house—no frozen shortcuts, ever.
• Community-Driven Culture: Antioch Pizza isn’t just about pizza—it’s about people. Our franchisees are active in their local schools, sports programs, nonprofits, and neighborhoods. We give back through fundraisers and events because we believe strong businesses build stronger communities.
• A Proven Model with Room to Grow: With strong brand recognition in the Midwest, Antioch Pizza is now expanding into the Southeast. That means South Carolina franchisees can benefit from our track record of success—while introducing something fresh to their local market.

Flexible Pizza Franchise Models to Fit Your Goals

Whether you’re opening in a downtown area like Charleston or in a growing suburb outside Greenville, we offer four flexible franchise models to suit different locations and budgets:

Full-Service Restaurant with Dine In / Takeout / Delivery 

Perfect for sit-down dining, carryout, and delivery, this model delivers the full Antioch Pizza experience.

• Franchise Fee: $40,000
• Estimated Startup Investment: $226,900 – $729,325

Full-Service Restaurant with  Takeout & Delivery 

Perfect for sit-down dining, carryout, and delivery, this model delivers the full Antioch Pizza experience.

• Franchise Fee: $40,000
• Estimated Startup Investment: $226,900 – $729,325

Express Restaurant

Ideal for smaller spaces and high-volume areas, Express shops focus on speed and convenience with a streamlined menu.

• Franchise Fee: $35,000
• Estimated Startup Investment: $108,500 – $352,900

Pizza Food Truck

Looking for maximum mobility? The food truck model brings our most popular menu items on the road to festivals, events, or business districts.

• Franchise Fee: $20,000
• Estimated Startup Investment: $106,500 – $196,825

Whichever model you choose, we provide full training, marketing support, and ongoing operational guidance to help you succeed.

Who We’re Looking For

The ideal Antioch Pizza franchise owner is someone who:

• Loves good food and enjoys serving their community
• Has restaurant experience OR a strong desire to learn
• Wants to be hands-on in growing a local business
• Cares about quality and values customer relationships

Whether you’re a seasoned restaurant operator or ready to make a career change, we’ll provide the tools and support you need to build something of your own. You bring the passion—we’ll bring the pizza.

Franchise a Pizza Shop in Charleston, Columbia, or Beyond

South Carolina’s mix of charming downtowns, family neighborhoods, and tourist hotspots makes it the perfect place to start your own Antioch Pizza Shop. You’ll introduce locals to an award-winning pizza brand known for doing things the right way—and become a hometown favorite in no time.

We are actively expanding in:

• Charleston (Mount Pleasant, North Charleston, Goose Creek)
• Columbia (Lexington, Irmo, West Columbia)
• Greenville (Simpsonville, Mauldin, Greer)
• Myrtle Beach (Conway, Surfside, North Myrtle Beach)
• Rock Hill & Fort Mill
• Summerville & Ladson
• Spartanburg & Anderson
• Hilton Head & Bluffton

Ready to Own a Pizza Franchise in South Carolina?

If you’re ready to take the next step, we’re ready to talk. Antioch Pizza is expanding across the Southeast, and South Carolina is next. Don’t miss your chance to own a pizza franchise in South Carolina with a proven brand that puts flavor and community first.